文章摘要
间歇冷却结晶过程的CFD-PBM数值模拟
Simulation of batch cooling crystallization process based on CFD-PBM
投稿时间:2022-04-03  修订日期:2022-04-29
DOI:
中文关键词: CFD-PBM耦合模型  冷却结晶  破碎模型  粒度分布
英文关键词: CFD-PBM coupling model  cooling crystallization  breakage kernel model  crystal size distribution
基金项目:国家自然科学(21808025,22078041);中央高校基本科研业务费(DUT20JC41)
作者单位邮编
覃渫兰 大连理工大学化工学院 116024
张磊 大连理工大学化工学院 116024
都健 大连理工大学化工学院 
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中文摘要:
      溶液结晶是一项重要的工业操作,被广泛应用于各个领域。针对扑热息痛-乙醇体系,结合计算流体动力学、结晶动力学和粒数衡算模型建立CFD-PBM耦合模型,模拟搅拌釜式结晶器中的间歇冷却结晶过程,与实验进行对比,模拟结果和实验结果有较好的一致性。探究晶种加入、搅拌速度、降温速率和破碎过程对粒度分布的影响,得出如下结论:适当加入晶种可以避免新晶体成核的高过饱和度,从而获得具有平均粒径大、颗粒数目多的粒度分布;采用合适的破碎模型,考虑更为全面的结晶动力学模型,能够提高产品粒度分布的预测能力;随着搅拌速度增大,颗粒数目增加,颗粒的平均粒径减小;线性降温曲线的降温速率越快,产生的颗粒数目越少,但颗粒的平均粒径增大。
英文摘要:
      Crystallization is an important industrial operation, which is widely used in various fields. A CFD-PBM coupling model was established to simulate the batch cooling crystallization process in stirred tank crystallizer for acetaminophen-ethanol system. The simulation results are in good agreement with experimental results. The effects of seed, stirring speed, cooling rate and breakage process on crystal size distribution were studied. Finally, the conclusions are as follows: proper addition of seed can avoid the high supersaturation caused by nucleation, and obtain the particle size distribution with large average size and large number of particles; the prediction of particle size distribution can be improved by adopting suitable breakage kernel model and considering more comprehensive crystallization kinetics model; with increase of stirring speed, the number of particles increases and the average particle size decreases; when cooling rate of linear cooling curve decreases, products with small particle number and large average particle size will be produced.
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